Quinacrine dihydrochloride

CAS No. 69-05-6

Quinacrine dihydrochloride ( —— )

Catalog No. M15645 CAS No. 69-05-6

An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Quinacrine dihydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years.
  • Description
    An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    DNA Alkylator
  • Recptor
    DNA; Histamine N-methyltransferase; PLA2; PLCLP
  • Research Area
    Cancer
  • Indication
    Prostate Cancer

Chemical Information

  • CAS Number
    69-05-6
  • Formula Weight
    472.88
  • Molecular Formula
    C23H30CLN3O·2HCl
  • Purity
    >98%(HPLC)
  • Solubility
    Ethanol: 28 mg/mL (59.21 mM); Water: 53 mg/mL (112.07 mM); DMSO: 14 mg/mL (29.6 mM)
  • SMILES
    [H+].[H+].[Cl-].[Cl-].CCN(CC)CCCC(C)NC1=C2C=C(OC)C=CC2=NC2=C1C=CC(Cl)=C2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Nuttle LC, et al. Am J Physiol. 1999 Apr;276(4 Pt 2):H1289-94.
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